Minimum Information About a Microarray Experiment - MIAME
MIAME describes the Minimum Information About a Microarray Experiment that is needed to enable the interpretation of the results of the experiment unambiguously and potentially to reproduce the experiment. [Brazma et al., Nature Genetics]
MIAME does not specify a particular format, however, obviously the data are more usable, if it is encoded in a way that the essential information specified by MIAME can be accessed easily. FGED recommends the use of MAGE-TAB format, which is based on spreadsheets, or MAGE-ML.
MIAME also does not specify any particular terminology, however for automated data exchange the use of standard controlled vocabularies and ontologies are desirable. FGED recommends the use of MGED Ontology for the description of the key experimental concepts, and where possible ontologies developed by the respective community for describing terms such as anatomy, disease, chemical compounds etc (see OBO page for more detail).
MIAME In Practice
There is a number of software tools supporting MIAME requirements under development.
These journals require MIAME compliant data as a condition for publishing microarray based papers.
ArrayExpress service to journals [PDF 508kb].
MIAME extensions or related activities
- MIBBI Project.
- MIAME CGH checklist [DOC 72kb] [PDF 61kb]
- MIAME ChIP-on-chip checklist [DOC 92kb] [PDF 64kb]
- MIAME proposal for random arrays [DOC 66kb] [PDF 141kb]
- MIAME/Tox and MIAME/Env
- MIAME/Plant Whitepaper: