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Mouse CD161 Antibody – Clone PK136

The Mouse CD161 Antibody – Clone PK136 is a mouse monoclonal antibody that specifically recognizes CD161 (NKR-P1C), a C-type lectin receptor predominantly expressed on NK cells and subsets of T cells in mice. This antibody is widely used in NK cell identification, depletion, and functional studies, particularly in C57BL/6 mouse models.

Product Overview

  • Name: Mouse CD161 Antibody – Clone PK136
  • Clone: PK136
  • Host species: Mouse
  • Reactivity: Mouse
  • Target: CD161 (NKR-P1C)
  • Receptor type: C-type lectin receptor on NK cells

Key Features & Benefits

  • Specific for mouse CD161 (NKR-P1C)
    Recognizes NK cell–associated receptor CD161, enabling accurate identification and monitoring of NK cell populations and certain T-cell subsets.
  • Ideal for C57BL/6 models
    Clone PK136 is particularly useful in C57BL/6 mice, where NKR-P1C expression is a key marker for NK cell analysis and functional assays.
  • Applications in immune regulation and cytotoxicity
    Suitable for studies on NK cell–mediated cytotoxicity, immune surveillance, immune regulation, and tumor immunity.
  • Versatile research tool
    Can be integrated into flow cytometry panels, in vivo depletion/activation strategies, and ex vivo functional assays involving NK cells.

Typical Applications

  • Identification and characterization of NK cells in mouse models
  • Flow cytometry immunophenotyping of NK cells and CD161⁺ lymphocytes
  • Studies of immune regulation, cytotoxicity, and tumor immunology
  • Functional experiments in C57BL/6 mouse strains involving NK cell activity